http://bugs.winehq.org/show_bug.cgi?id=24101
--- Comment #9 from Dan Kegel dank@kegel.com 2010-08-24 07:13:55 --- Did you increase ulimit properly, though? It's kind of tricky:
sudo bash ulimit -n 10000 su $LOGNAME
(or maybe $USERNAME instead of $LOGNAME) That will give you a shell with a raised file descriptor limit.