https://bugs.winehq.org/show_bug.cgi?id=44504
--- Comment #5 from Henri Verbeet hverbeet@gmail.com --- (In reply to Paul from comment #3)
hardware/driver is all that would've stayed constant. I'm using GTX 660 card
- nvidia driver 384.111 right now on Mageia.
This never really worked on propritary NVIDIA, so unless you have a reason to avoid Nouveau, you're probably better of with that driver, generally speaking.
As for the regression though, does just restoring the XFlush() in X11DRV_ExtEscape() also restore the old behaviour for you?