https://bugs.winehq.org/show_bug.cgi?id=44525
--- Comment #6 from Timur Kristóf venemo@msn.com --- Reproduced the same issue with The Witcher 1 (from GOG). Otherwise works well on Xorg, but produces weird behaviour on Xwayland. It seems that it gets incorrect mouse input (ie. no matter how I move the mouse, the camera viewport always moves in a fixed way, as if it didn't actually know which direction I moved the mouse).
Could possibly be a bug in Xwayland or libinput (or wine?).