https://bugs.winehq.org/show_bug.cgi?id=51301
--- Comment #4 from gnuwho.gnuwho@gmail.com --- (In reply to Ho Tuan Dat from comment #3)
This buggy mouse can be fixed by building from sources,you can follow the fandom instructions to fix this.
The fix on the RoL fandom is not a proper fix, and is a janky one that would break other games as well.