https://bugs.winehq.org/show_bug.cgi?id=45046
--- Comment #3 from Jarrard Lo overlord.jarrard@gmail.com --- (In reply to Jarrard Lo from comment #2)
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Unfortunately I can't get any of the mod managers to work correctly so looks like I will need a VM to do the mod install process (for testing).
PS. Yes SKSE64 and FO4 Script extenders work for me!