http://bugs.winehq.org/show_bug.cgi?id=31113
--- Comment #124 from lorian.grace@gmail.com --- (In reply to Von Random from comment #123)
Can you tell more about hardfile? What is this?
The post you've quoted is pretty much self explanatory. Hardfile means a disk image in a file. Basically, a file that contains a filesystem and can be mounted for reading / writing as a loop device.
Well, I did it, but how do you run the game afterwards? I tried to do it from the folder in civ5.loopdir, but it crashed.