[Bug 21105] RealMYST 1.11: Fails to start (Possible D3D issue)

http://bugs.winehq.org/show_bug.cgi?id=21105

--- Comment #7 from GyB  2013-01-23 12:25:14 CST ---
> fixme:vxd:__wine_vxd_open Unknown/unsupported VxD L"siwvid.vxd". Try setting Windows version to 'nt40' or 'win31'.
> fixme:vxd:__wine_vxd_open Unknown/unsupported VxD L"ntice.vxd". Try setting Windows version to 'nt40' or 'win31'.
> ...

Did you try that?

You should check the game with a tool like ProtectionId to find out what
copy-protection it uses.
> ...also changed my graphics card to an Nvidia since the original bug report.

from your log:
> fixme:d3d_caps:wined3d_guess_card No card selector available for GL vendor 0x4 and card vendor 0000 (using GL_RENDERER "Gallium 0.4 on llvmpipe (LLVM 0x300)").

Doesn't look like it's configured correctly. Could you try the binary drivers?