http://bugs.winehq.org/show_bug.cgi?id=58513
--- Comment #19 from xeroxslayer@proton.me --- OK, I can confirm that that commit `745a11a231816a7d82490156c72a18c39216a14c` is the problematic one. Building with it makes a broken Wine install on that rig, building without it makes winecfg update the index and the config window pops up just fine. Winamp runs fine as well.
So, what's the next step? Clone, then merge `mr-8591` and see if it works?