https://bugs.winehq.org/show_bug.cgi?id=56013
--- Comment #3 from m1m1k4tz m1m1k4tz@protonmail.com --- (In reply to alexandros.frantzis from comment #2)
It seems Wine is trying use OpenGL, I guess through WineD3D. However OpenGL support is not implemented yet in the Wayland driver (only Vulkan, that's why DXVK works).
That makes sense. I'm not sure if the crashing to lock screen when exiting the launcher might lead to a bigger issue, but the crash doesn't happen when the game exits after launch so it isn't really a huge deal for playability imo