http://bugs.winehq.org/show_bug.cgi?id=19811
--- Comment #2 from Austin English austinenglish@gmail.com 2009-08-21 21:31:32 --- (In reply to comment #0)
Attempting to install various versions of VS 2005 vcredist_x86.exe in a fresh prefix creates directories in WinSXS for all versions described by the policies.
Only the directory for the current version (described by the manifest) has DLL files in it, all others are empty.
Have you tested windows to see what happens there?