https://bugs.winehq.org/show_bug.cgi?id=50221
--- Comment #3 from serge@stroobandt.com --- Thanks, Oliver.
For the sake of completeness, I run PlayOnLinux 4.3.4 and winetricks 0.0+20200412-1 on top of wine. This method has served me well with wine 3.20 as it avoids standalone wine "wining" about missing DLLs.
The debug information I was able to get from PlayOnLinux is shown below:
Running wine-4.21 4nec2.exe (Working directory : /home/serge/.PlayOnLinux/wineprefix/4nec2/drive_c/4nec2/exe) 0016:err:ntoskrnl:ZwLoadDriver failed to create driver L"\Registry\Machine\System\CurrentControlSet\Services\NDIS": 00000001 000f:fixme:service:scmdatabase_autostart_services Auto-start service L"NDIS" failed to start: 731 0021:err:ntoskrnl:ZwLoadDriver failed to create driver L"\Registry\Machine\System\CurrentControlSet\Services\wineusb": c0000142 000f:fixme:service:scmdatabase_autostart_services Auto-start service L"wineusb" failed to start: 1114 0009:fixme:ole:OaBuildVersion Version value not known yet. Please investigate it ! 0009:fixme:olepicture:OleLoadPictureEx (00EF02F4,61616,1,{7bf80980-bf32-101a-8bbb-00aa00300cab},x=0,y=0,f=0,0032F7A0), partially implemented. 0009:err:wincodecs:JpegDecoder_CreateInstance Failed reading JPEG because unable to find libjpeg.so.62 0009:fixme:ole:CoCreateInstanceEx no instance created for interface {9edde9e7-8dee-47ea-99df-e6faf2ed44bf} of class {9456a480-e88b-43ea-9e73-0b2d9b71b1ca}, hres is 0x80004005 0009:err:olepicture:OleLoadPictureEx IPersistStream_Load failed