https://bugs.winehq.org/show_bug.cgi?id=39663
--- Comment #9 from fjfrackiewicz@gmail.com --- (In reply to Nathan from comment #8)
Wine 1.9.11 setup_galaxy_1.1.11.53.exe
Based on suggestions by others, I installed via winetricks: gdiplus Also vcrun2015
added native,builtin overrides for: ucrtbase api-ms-win-crt-heap-l1-1-0 api-ms-win-crt-locale-l1-1-0 api-ms-win-crt-runtime-l1-1-0 api-ms-win-crt-stdio-l1-1-0 vcruntime140 msvcp110 msvcr110
GOG Galaxy crashes mentioning libcef.
Try running Galaxy in Windows XP mode. Sometimes that helps :)