https://bugs.winehq.org/show_bug.cgi?id=10845
--- Comment #31 from schroedingerscat@disroot.org ---
That would mean this bug was fixed at some point, and then broke.
I think there was only a patch that would have fixed it. But the patch didn't get accepted. However, comment 18 (https://bugs.winehq.org/show_bug.cgi?id=10845#c18) then mentions that there's the workaround of pressing Alt+Arrow Key Down. Probably nobody before comment 18 thought of that, so they likely all stated "Reason's Main Menu doesn't work" because the way most people try to interact with the main menu is using the mouse. That's how I interpret the conversation.
My addition to the conversation however is: that workaround of pressing Alt+Arrow Key Down worked until Wine v10.0-rc5 but is now broken as of Wine v10.0-rc6.
I ran a regression test and the workaround stopped working at git commit 710b94e212501727b3b1b8deea06a7757df43d51