http://bugs.winehq.org/show_bug.cgi?id=30226
--- Comment #2 from Vitaliy Margolen vitaliy-bugzilla@kievinfo.com 2012-03-19 20:34:57 CDT --- Most likely missing registry entries is the culprit that this software can't find serial ports. Look at +reg debug output to see where your program probing and for what.