http://bugs.winehq.org/show_bug.cgi?id=14446
--- Comment #10 from Austin English austinenglish@gmail.com 2009-01-22 08:07:21 --- (In reply to comment #9)
(In reply to comment #8)
rm .wine/*.reg
Why would you do that?
If you want to use a clean prefix, remove ~/.wine, not ~/.wine/*.reg.
Uhu, so remove the whole .wine folder?
Yes.
Does this mean, the entries in the Desktop are removed as well?
No, you'd have do that manually (same for Applications menu).