https://bugs.winehq.org/show_bug.cgi?id=51172
--- Comment #1 from Zebediah Figura z.figura12@gmail.com --- Can you please list specific games? "Most games" doesn't help very much.
Can you please try compiling with one or more of d3d11-Deferred_Contexts, nvapi-Stub_DLL, or wined3d-CSMT_Main disabled? Those are the most likely candidates for what's causing the problem.