http://bugs.winehq.org/show_bug.cgi?id=19036
--- Comment #2 from Antonio López amlopezalonso@gmail.com 2009-06-22 17:51:31 --- As I said, I have disabled desktop effects, so no 3d gadgets :-).
Notepad is not a good app for testing this case as the bug only happens (I forgot mentioning it) when running apps in full screen.
With a new WINEPREFIX I have tried The Bard's Tale and the bug is still there. In this case I also had to logout, delete krandrrc and then relogin to tidy up the screen resolution.