http://bugs.winehq.org/show_bug.cgi?id=27917
--- Comment #7 from Andrew Eikum aeikum@codeweavers.com 2011-07-27 12:12:33 CDT --- Okay, cool. The Civ V issue is a separate bug. Audio should work regardless of the acceleration setting. (To be honest, I would really like to remove the Full Acceleration setting entirely. It's a leftover from the old architecture and creates confusion and conflicting bug reports.)
If you're interested in helping fix the Civ V Emulation mode bug, creating a new bug with the same log channels with dsound in emulation mode would be helpful.