http://bugs.winehq.org/show_bug.cgi?id=31860
--- Comment #9 from Samuel Nelson valczir.darkvein@gmail.com 2012-10-03 09:38:22 CDT --- Just FYI, I use many different window managers (and a couple of desktop environments), and GW2 works the same across all of them. I don't think it's that.
sworddragon2: I'm curious if it was working any better with any previous versions of Wine. I don't know how ubuntu works these days (they lost my interest when they included networkmanager before it was ready, way back when I was in college), but if it's possible, could you try to install previous versions of Wine through your package manager?
If ubuntu doesn't have packages for earlier versions of Wine, could you install PlayOnLinux and try to download a few different versions of Wine (I'm most specifically interested in 1.5.9 and up, including the -GuildWars2 versions), then try launching GW2 with them and see if anything changes?
Also, try changing to windowed fullscreen or windowed mode and let us know if that changes anything.