http://bugs.winehq.org/show_bug.cgi?id=9457
--- Comment #1 from Roderick Colenbrander thunderbird2k@gmx.net 2007-08-25 14:40:14 --- Wine needs to be compiled as 32bit. It won't work as a 64bit program. In short windows programs are 32bit, a 64bit Wine would only be able to run 64bit programs and for which we don't have support (yet).
I have no FreeBSD experience but it means that you need to install 32bit libraries, compiler and so on. Further I believe that there are serious problems running Wine on FreeBSD. For proper Wine support on FreeBSD you need I think the latest kernel with 'thr_kill2' support. Further you need Wine 0.9.44 with some patches. I think I saw those on wine-patches but those haven't been committed yet. You would need to apply them yourself.
So get 32bit stuff and you also need to upgrade your kernel and more if you want to run Wine.