http://bugs.winehq.org/show_bug.cgi?id=22572
--- Comment #8 from Vincent Povirk madewokherd@gmail.com 2011-02-25 16:00:10 CST --- It seems Mono only loads assemblies with the OS loader if ENABLE_COREE is defined, and my builds do not have that defined (the default), but the official Windows builds do. If it's not loaded by the OS loader, then there's no chance of native code working. ENABLE_COREE also causes Mono to hook mscoree.dll, replacing many of its functions. I don't think we want this.
I need to understand better how Mono's coree code works before I can say how to resolve this.