https://bugs.winehq.org/show_bug.cgi?id=57215
--- Comment #9 from Hanabishi i.r.e.c.c.a.k.u.n+bugs.winehq.org@gmail.com --- Don't worry. For the last few releases, I intentionally search for regressions across all apps I have.
In fact, after seeing winex11/OpenGL-related stuff in the changelog, I predicted that it would affect something and immediately went testing RA2. And it actually did.