https://bugs.winehq.org/show_bug.cgi?id=43118
--- Comment #6 from Emil Lauridsen mine809@gmail.com --- Okay, color me intrigued.
The issue appeared to be CSMT... Disabling it seemingly improved performance in many scenarios, and the profile spread seems a lot more reasonable:
samples| %| ------------------ 1379086 38.4584 anon (tgid:12143 range:0x140001000-0x141016fff) 973754 27.1550 libnvidia-glcore.so.381.22 449930 12.5471 wined3d.dll.so
With the top one probably being the game (please correct me if I'm wrong), then the proprietary GL impl and then wined3d in third place.
Performance is seemingly rather close to native windows performance, although I have yet to test performance doing raiding, which is more intensive, but initial result is promising.