http://bugs.winehq.org/show_bug.cgi?id=22916
--- Comment #6 from Andrew Nguyen arethusa26@gmail.com 2010-05-28 12:46:46 --- (In reply to comment #5)
For what it's worth, you can try Mono (it works in Wine and supports .NET 3.5): http://wiki.winehq.org/Mono
Hmm, does it? I thought .NET 3.5 support in Mono was slated for the far future. In any case, the app relies on the Windows Presentation Foundation, which isn't implemented in Mono currently.