https://bugs.winehq.org/show_bug.cgi?id=46976
kotrigmd@gmail.com changed:
What |Removed |Added ---------------------------------------------------------------------------- CC| |kotrigmd@gmail.com
--- Comment #28 from kotrigmd@gmail.com --- I managed to work around this issue by re-enabling processor C-states in BIOS, after having previously disabled them. I noticed in sysprof that switching the CPU to an idle state was taking up a massive amount of time whenever I moved my mouse (or pressed a lot of keys at the same time), during which the game I had open would completely stall, so from there I had a pretty good guess as to what was going on.
That said, the fact that this only happens in wine, and not in Windows or any native programs, seems possibly indicative of a deeper problem with wine itself. It's also possible that what fixed it for me won't fix it for everyone else.