[Bug 49579] New: Running .exe from programs with GUI uses wrong prefix in Wine 5.0

[WineHQ Bugzilla]

https://bugs.winehq.org/show_bug.cgi?id=49579

Bug ID: 49579
           Summary: Running .exe from programs with GUI uses wrong prefix
                    in Wine 5.0
           Product: Wine
           Version: unspecified
          Hardware: x86
                OS: Linux
            Status: UNCONFIRMED
          Severity: minor
          Priority: P2
         Component: -unknown
          Assignee: [e-mail]
          Reporter: [e-mail]
      Distribution: ---

When running an *.exe by doubleclicking on it in the fileexplorer (Thunar),
Wine 5.0 will not run it in the standard prefix ~/.wine as it should, but
instead in another existing prefix in ~/.local/share/wineprefixes/wine32.
Winetricks shows the same behaviour, opening wine32 when told to open the
standardprefix - though for some reason, it also shows wine32 among the
secondary prefixes, while not showing wine at all.
Running from console will produce the expected outcome of running in ~/.wine.

This did not happen in Wine 4.0, and started happening immediately after the
update to Wine 5.0, without any configuration changes.
I've already checked .bash-rc and .profile and made sure there's no value set
for $WINEPREFIX.

While not exactly a major bug, it's a bother to work around for every single
program.

OS: Linux Mint 20 Xfce
Wine: 5.0-3