http://bugs.winehq.org/show_bug.cgi?id=26021
--- Comment #2 from Nikolay Sivov bunglehead@gmail.com 2011-02-07 18:19:29 CST --- Specify wine version please. This could be caused by installed service (that some application did install in your wine prefix), try to remove .wine and start from a scratch to see if winecfg starts up fine.