http://bugs.winehq.org/show_bug.cgi?id=27867
--- Comment #6 from Alexey Kuznetsov ak@axet.ru 2011-12-17 18:34:03 CST --- skyrim ran on lowwest settings. mouse issue still here.
it is similar to your explanation - you have to move mouse really slow to point in the right dirrection but it not just really slow it mixes with coordinates.
like you move mouse straigth up and screen moves in left up or similar effect.