https://bugs.winehq.org/show_bug.cgi?id=40625
--- Comment #6 from Bruno Jesus 00cpxxx@gmail.com --- AFAIR Photoshop 4 was the last 16-bit one, but maybe if some component in Photoshop 6 is still 16-bit the trouble may be due to the 16-bit changes made in the kernel from 3.14 onwards.
http://news.softpedia.com/news/Linux-Kernel-3-14-Breaks-Wine-for-16-bit-Wind...
But there is a kernel flag introduced in 3.16 to make it work again.