https://bugs.winehq.org/show_bug.cgi?id=42319
--- Comment #5 from winetest@luukku.com --- You are running the dx10/11 version of the game.
fixme:gameux:GameExplorerImpl_VerifyAccess (0x156fe8, L"C:\Program Files\Ubisoft\Ubisoft Game Launcher\games\Assassin's Creed 1\AssassinsCreed_Dx10.exe", 0x33f758)
cd into that directory and start the exe with dx9 in the name.