http://bugs.winehq.org/show_bug.cgi?id=25708
--- Comment #7 from Scott Ritchie scott@open-vote.org 2011-01-09 18:21:17 CST --- .wine is created after Wine runs...in your case it's crashing before even getting there.
I'm not saying you should backup/reinstall immediately, I'm saying you should test booting off a stick to see if that works. If so we can rule out Wine and you can take your problem to askubuntu.com, which is better help than me.