https://bugs.winehq.org/show_bug.cgi?id=43613
unsuspicious.fakename+wine@gmail.com changed:
What |Removed |Added ---------------------------------------------------------------------------- CC| |unsuspicious.fakename+wine@ | |gmail.com
--- Comment #2 from unsuspicious.fakename+wine@gmail.com --- Still happens with wine staging 2.20 / SPAZ2 1.0
The 3d view cursor (/targeting reticle) and the ingame GUI mouse pointer somehow become "detached" from each others which leaves one of them stuck (usually to the screen border).
WORKAROUND: Alt+tabbing out of the game and back switches control to the mouse pointer that belongs to the currently active "viewport" (which is easier with a virtual desktop but works either way). This has to be done every time after switching between 3D and UI control though.