https://bugs.winehq.org/show_bug.cgi?id=51697
--- Comment #14 from Gabriele gab.pulcio@gmail.com --- (In reply to Alexey Kuznetsov from comment #13)
Another possibility: since those lags not related to file operations (I ran +file) and lags persist during PHOTO MODE (when no physics and quests calulated) and during in-game video it could be Far Cry 5 EasyAntiCheat service activity.
If you disable the HD texture pack the problem will go away, the problem is: why? It doesn't even fill my VRAM, something is clearly wrong.