https://bugs.winehq.org/show_bug.cgi?id=41235
--- Comment #2 from Tobias (:Tobbi) Markus tobbi.bugs@googlemail.com --- (In reply to Martin Fuhrer from comment #1)
This appears to be a more general problem in the latest wine releases (I encountered it in 1.9.16). Running any executable that attempts to open a window (e.g. winemine, regedit) fails to do so, generating the "Application tried to create a window, but no driver could be loaded" console error.
Another forum thread about the problem is here: https://forum.winehq.org/viewtopic.php?f=9&t=27305
Martin and others: I just re-installed wine via homebrew (as opposed to Macports, previously) and things have started to work again. I am not sure if this has something to do with one of the releases in the meantime or whether it's a bug with how Macports installs wine.
Can you re-test?