https://bugs.winehq.org/show_bug.cgi?id=46677
--- Comment #1 from Matteo Bruni matteo.mystral@gmail.com --- 012e:err:winediag:wined3d_dll_init Setting multithreaded command stream to 0. 012e:err:winediag:wined3d_dll_init Setting multisample textures to 0.
Does it make any difference if you get rid of these two settings?