http://bugs.winehq.org/show_bug.cgi?id=19182
--- Comment #26 from André H. nerv@dawncrow.de 2010-11-29 10:13:30 CST --- (In reply to comment #25)
Using registry for setting this option isn't the best idea, because a user might not have ~/.wine at all when he'd like to install a new application.
Then the user can run regedit before...
A environment variable would most likely look like WINEDESKTOPINTEGRATION, but also i doubt it will happen