https://bugs.winehq.org/show_bug.cgi?id=39225
--- Comment #5 from James Smith jlsmi3th@gmail.com --- This error happened when I tried to run /Home/.wine/drive_c/IRTI/Setup.exe again:
1608: Unable to create InstallDriver instance, Return code: -2147221164
I downloaded the zip file, copied it to /Home/.wine/drive_c/, ran the extract with the option to recreate directory structure, then failure happened.