http://bugs.winehq.org/show_bug.cgi?id=25049
--- Comment #2 from awesome ilyakon@gmail.com 2010-11-06 10:56:18 CDT --- Before installation Mathcad 12 looks for a mdac_26 or newer and MSXML 4.0 or newer. If you don't have them, Mathcad installs required components automatically.
Yes, I tried winetricks for your advice but nothing changed.