http://bugs.winehq.org/show_bug.cgi?id=6297
--- Comment #29 from James Andrewartha trs80@ucc.asn.au 2007-12-03 02:45:06 --- (In reply to comment #28)
I'm getting this problem with TF2 incessantly with 0.9.50. I have not been able to find a workaround, other than rebooting my PC.
Does chattr -R +S on Steam/SteamApps/<username> not work for you?
Is this problem caused solely by the "clientregistry.blob" file? Deleting the file and restarting steam (with wineboot command as well) does not fix anything for me.
No, I don't think it has anything to do with ClientRegistry.blob, and that deleting it only works because it flushes some other files out of the cache due to all the activity generated by recreating it.
Something to try would be to dumping your caches as described at http://linux-mm.org/Drop_Caches i.e. run "sync; echo 3 > /proc/sys/vm/drop_caches"