http://bugs.winehq.org/show_bug.cgi?id=23014
--- Comment #3 from Andrew Nguyen arethusa26@gmail.com 2010-06-03 03:40:05 --- (In reply to comment #2)
A WINEDEBUG=+msi trace might help to determine which 4.5 functions this installer needs.
It didn't appear to require anything specific to Windows Installer 4.5, as I did manage to get the application installed without issue. Installing did expend more disk space (about 10 GB) than what I would have expected from the installer's expected disk usage, which is slightly concerning to me.