https://bugs.winehq.org/show_bug.cgi?id=24653
--- Comment #14 from Bartosz gang65@poczta.onet.pl --- @C. Leu Unfortunately I was not able to install Paint.NET 3.5 (Paint.NET 3.0 is working perfectly without lag).
Could you run Paint.NET 3.5 with WINEDEBUG, and attach logs from it:
WINEDEBUG=+timestamp,+gdiplus wine PaintDotNet.exe