http://bugs.winehq.org/show_bug.cgi?id=27156
--- Comment #55 from Alexandre Julliard julliard@winehq.org 2011-05-30 12:39:13 CDT --- (In reply to comment #54)
Yes, that's why I think it would be interresting to be able to configure whether or not to use XInput2 on a per application basis, just like MouseWarpOverride.
You can set the GrabPointer option in HKCU/Software/Wine/X11 Driver.