https://bugs.winehq.org/show_bug.cgi?id=54941
--- Comment #1 from Francisco Casas fcasas@codeweavers.com --- The workaround is to create a new prefix and manually relativize the symlink paths:
wine64/loader$ rm wine-preloader wine64/loader$ ln -s ../../wine32/loader/wine-preloader wine-preloader wine64/loader$ rm wine wine64/loader$ ln -s ../../wine32/loader/wine wine