http://bugs.winehq.org/show_bug.cgi?id=29647
--- Comment #8 from Henri Verbeet hverbeet@gmail.com 2012-02-24 03:57:11 CST --- (In reply to comment #5)
Swapping in an NVidia 8800GTX card resolves the issue so it does appear to be, as Henri said, a fglrx issue.
Is there anything else to try or should this be reported to AMD?
For reporting the issue, it may help if you're able to reproduce it with a small GL application outside of Wine as well. But well, fglrx. It may also be worth giving the r600g driver a try if you haven't already.