https://bugs.winehq.org/show_bug.cgi?id=54628
--- Comment #2 from C. Leu kle@bluewin.ch --- A new addition.
After I found a Linux question about this problem on reddit (https://www.reddit.com/r/linuxquestions/comments/qyxkpf/docx_files_leads_to_...), it looks that this might be in the end an issue of xdg-open and not Wine.
So there exist now also a bug report at xdg-utils GitLab page: https://gitlab.freedesktop.org/xdg/xdg-utils/-/issues/216