https://bugs.winehq.org/show_bug.cgi?id=47364
--- Comment #4 from Rick Stanback rick@tripletry.com --- to reproduce the problem download putty from the internet and run via wine putty configure a serial port and try to open the connection.
UPdate: I built the latest GIT build wine-4.10-154-gc674ceefe1 and it appears to be working now.
I am not sure how to do the regression testing to see which patch caused the problem. I have not decide if I want to install this build or just wait til the next update from fedora repo.