http://bugs.winehq.org/show_bug.cgi?id=23127
--- Comment #5 from Austin English austinenglish@gmail.com 2011-01-13 17:23:25 CST --- (In reply to comment #2)
Oh, and if you let the window lose focus, then even in virtual desktop mode, keystrokes are ignored, and you can't start the game.
I can confirm that, though the patch from bug 23643, fixes it for me.
But the original bug I can't confirm. Please retest.