https://bugs.winehq.org/show_bug.cgi?id=33290
--- Comment #19 from Gabriel Corona gabriel.corona@enst-bretagne.fr --- The current patch breaks multihead so it won't get merged. The problem seems to be in the nvidia driver anyway so we might want to try to have this bug fixed there.
For now, you should be able to use UseXRandR=N. Another possible workaround might be to force xrandr 1.0 somehow.