https://bugs.winehq.org/show_bug.cgi?id=47189
--- Comment #9 from logicalman101@gmail.com --- (In reply to Fabian Maurer from comment #7)
I even tried wiping out the whole wineprefix and recreating it. If I try to install dotnet462 it fails because it has dotnet40 installed even though I never told it to do that with the new prefix.
Then you didn't wine it properly. Just deleting the .wine folder is enough though. Btw, Vortex doesn't seem to need the .NET framework at all, it works for me without. And yes, I only tested with wine-4.8, can you try that, too?
I upgraded to 4.8.1 via building from source but it still didn't help I added an attachment of the output I get from terminal when I try to install Vortex. I also found two lutris scripts prior but neither worked and I wound up making this issue on the lutris github. https://github.com/lutris/lutris/issues/2133