http://bugs.winehq.org/show_bug.cgi?id=17333
--- Comment #7 from Stefano Guidoni s.guidoni@tin.it 2009-09-26 13:13:42 --- I can confirm that irisu syndrome doesn't work with nvidia hardware. Tested on wine 1.1.30, nvidia geforce g 103m, driver v.185.18.31.
P.S.: it still works on ati radeon 9250 with open source drivers.